Patent

2. Le, H. V.; Paris, J. R.; Mahdi, F.; Khan, M. I. H.; International/U.S. Patent Application PCT/US2022/075220 (filed August 19, 2022). Allopregnanolone Analogues for HIV Viremia and Neurotoxicity Protection.

1. Le, H.V.; Kim, S.J.; Khan, M.I.H; UM 9320 - US Provisional (2022) Cytochrome bc1 Complex Inhibitors and Methods of Use Thereof

 Peer-reviewed Manuscripts

10. A mild and catalyst-free α-benzoyloxylation of tertiary amides

Khan, M.I.H.; Yang, J.; Kim, S.J.; Le, H.V.;  

Medicinal Chemistry Research, 2025

9. Chemical structure-biological activity of 1,4-naphthoquinone analogs as potential Aedes aegypti larvicides

Kim, S.J.; Khan, M.I.H.; Alden, S.; Charles, L.; Le, H.V.; 

Pest Management Science. 2025

8. PAX3-FOXO1 uses its activation domain to recruit CBP/P300 and shape RNA Pol2 cluster distribution. 

Asante, Yaw.; Benischke, K.; Issra. O.; Ngo, Q.A.; Wurth, J.; Laubscher, D.; Kim, H.; Udhayakumar, B.; Khan, M.I.H. et al.; 

Nature Communications. 2023, 14, 8361  

7. Alleviation of Cocaine Withdrawal and Pertinent Interactions between Salvinorin-based Antagonists and Kappa Opioid Receptor

Akins, N.S.; Mohammed, S.F.; Pandey, P.; Kim, S.J.; Mahdi, F.; Khan, M.I.H.; Moss, E.; Worth, C.; Keanne, M.M.; Chittiboyina, A.G.; Doerksen, R.J.; Paris, J.J.; Le, H.V.;*

ACS Chemical Neuroscience; 2023, 14, 5, 958–976

6. Two Phthalate and Terephthalate Plasticizers Unprecedently Isolated from Capparis spinosa L. Leaves.

Kdimy, A.; Kim, S.J.; Ali, Z.; Khan, M.I.H.; Tripathi, S. K.; Hajjaji, S.E.;* Le, H.V.;*

Chemistry and Biodiversity; 2023, 20, e2023009

5. Synthesis and Biological Evaluation of tert-Butyl Ester and Ethyl Ester Prodrugs L-γ-Methyleneglutamic Acid Amides for Cancer. 

Khan, M.I.H.; Mahdi, F.; Penfornis, P.; Akins, N.S.; Hossain, M.I.; Kim, S.J.; Sulochana, S.P.; Adam, A.T.; Tran, T.D.; Tan, C.; Claudio, P.P.; Paris, J.J.; Le, H.V.;* 

Bioorganic and Medicinal Chemistry 2022, 78, 117137

4. A Comprehensive and Systematic Review on the Kappa Opioid Receptor and Its Ligands: New Directions for the Treatment of Pain, Anxiety, Depression, and Drug Abuse. 

Khan, M.I.H.; Akins, N.S.; Sawyer, B.J.; Le, H.V.;*

European Journal of Medicinal Chemistry; 2022, 243, 114785. 

3. Synthesis of 3,4,5-Trisubstituted Isoxazoles in Water via a [3+2]-Cycloaddition of Nitrile Oxides and 1,3-Diketones, β-Ketoesters, or β-Ketoamides: Base-mediated and Keto-enol-controlled Mechanism. 

Hossain, M.I.; Khan, M.I.H.; Kim, S.J.; Le, H.V.;*

Beilstein Journal of Organic Chemistry; 2022, 18, 446-458. 

2. Methanol Extract of Solanum Violaceum Root Possesses Antiobesity, Hypolipidemic, Thrombolytic, and Membrane Stabilizing Activity; 

Ahamed, S.K.; Khan, M.I.H.; Billah, M.M.; Hossain, M.S.;*  

Journal of  Research in Pharmacy, 2017, 22,1. DOI : 10.12991/mpj.2018.47

1. Cytotoxic and antibacterial naphthoquinones from an endophytic fungus, Cladosporium sp.; 

Khan, M.I.H.; Sohrab, H.; Rony, S.R.; Tareq, F.S.; Hasan, C.M.; Mazid, M.A.;*  

Toxicology Reports; 2016, 3, 861-865.

Book Chapter

1. Book Title: Medicinal Chemistry of Chemotherapeutic Agents; Chapter: Antimalarial drugs; 

Sawyer, B.J.; Khan, M.I.H.; Le, H.V.;

Elsevier Academic Press 2022; ISBN: 9780323905756  

In preparation (8)

8. Design, synthesis, and structure-activity relationships of (Phenoxyphenyl)-1,4-Naphthoquinone-based compounds against methicillin-resistant S. aureus.

Khan, M.I.H.; Kim, S.J.; Tripathi, S.K..; Khan, S.I.; Le, H.V.*  

7. Development of a novel Salvinorin-Based Selective Kappa Opioid Receptor Agonist. 

Khan, M.I.H.; Kim, S.J.; Roth, B; Le, H.V.*  

6. Synthesis and biological evaluation of novel PET imaging agent. 

Khan, M.I.H.; Hossain, M.I.; Butch, E.R.; Snyder, S.E.; Le, H.V.;

5. Tetrazole derivatives of Salvinorin as dual agonist of KOR and MOR.

Khan, M.I.H; Akins, N.S.; Kim, S.J.; Le, H.V.* 

4. Cytotoxicity of Naphthoquinone-based Compounds in Human Cancer Cell Lines.

Khan, M.I.H.; Kim, S.J.; Khan, S.I.; Le, H.V.* 

3. Novel 2-Hydroxy-1,4-naphthoquinones as Drug-resistant Antimalarials and Antibacterials. 

Kim, S.J.; Li, Y.; Mahoney, A.R.; Khan, M.I.H.; Tripathi, S.K.; Khan, S.I.; Wuest, W.M.; Riscoe, M; Le, H.V.;*   

2. Discovery of allopregnanolone-based analogue as a neuroprotective agent against HIV. 

Khan, M.I.H.; Mahdi, F.; Elhanafy,  E.; Salahuddin, M.F.; Akins, N.S.; Kim, S.J.; Li, J.;* Paris, J.J.;* Le, H.V.* 

1. Discovery of allopregnanolone-based analogue as an anti-viremic agent against HIV. 

Mahdi, F.; Elhanafy, E.; Khan, M.I.H.; Akins, N.S.; Kim, S.J.; Li, J.;* Paris, J.J.;* Le, H.V.*