Synthetic Organic Chemistry:
- Efficient synthetic scheme design,
- Multi-step synthesis,
- chemical method optimization,
- experienced with different scaffolds such as naphthoquinone, carbazole, steroidal, isoxazole, amine acid, salvinorin, fusarubin, etc.
- Experienced with stereospecific steroidal, naphthoquinone, and salvinorin analogs.
Medicinal Chemistry:
- Rational and Structure-based drug design
- Computer-aided drug design
- Lead discovery and optimization process
- Data collection and interpretation
- Literature search
- Medicinal chemistry-associated software
Natural product chemistry:
- Extraction of endophytic fungi from plants,
- Secondary metabolites isolation and characterization from both fungi and plants,
- chemical modification and derivatization of natural products.
Computational Chemistry:
- Computer aided drug design,
- protein visualization,
- ligand preparation,
- protein preparation,
- homology modeling,
- virtual screening,
- glide docking,
- induced-fit docking,
- covalent docking,
- ADME-T prediction,
- molecular dynamic (MD) simulation,
- ligand-protein interaction visualization and image generation.
Analytical Techniques: Column chromatography, thin-layer chromatography (TLC), preparative TLC, analytical high-performance liquid chromatography (HPLC), preparative HPLC, liquid chromatography-mass spectrometry (LC-MS), nuclear magnetic resonance (NMR) spectroscopy.
Softwares and Databases:
Sci-finder, MestReNova, ChemDraw, bioRender, bioinformatics and cheminformatics database such as TCGA cBioPortal, UniProt, PDB, PubChem, MolPort, ZINC15, DrugBank, GtoPdb etc; Computation tools such as Schrodinger suite, GOLD, SWISS-MODEL, VMD, NAMD.